Jun 10, 2025 · The resulting dopamine deficiency disrupts the motor system, leading to hallmark symptoms such as tremor, rigidity, akinesia, and postural instability (TRAP).

Apr 26, 2024 · These five things to know about diagnosis, quality of life, and management in Huntington disease are crucial for effective care of patients with this devastating …

Mar 25, 2025 · In PD, motor symptoms, such as bradykinesia, rigidity, and instability, overlap with key components of physical frailty. Frail patients with PD may exhibit more pronounced …

Nov 29, 2023 · TOPLINE: Stimulating the vagus nerve reduced orthostatic tachycardia in patients with postural tachycardia syndrome (POTS), possibly through decreased antiadrenergic …

Dec 23, 2025 · Newer therapies improve inflammatory rosacea, yet additional research is needed to help clinicians manage vascular, neurogenic, and other challenging phenotypes.

Dec 23, 2025 · Targeted clinical review during a high-risk phase of care allows early intervention and prevents patient deterioration, thus reducing potential hospital admission.

Dec 17, 2025 · Overreliance on D-dimer testing and similarity to other conditions may mean pulmonary embolism or venous thromboembolism is missed in pregnant women.

May 13, 2025 · While GLP-1 receptor agonists and bariatric surgery offer significant metabolic benefits, experts caution that rapid weight loss may trigger emotional instability in vulnerable …

PSP patients with the Richardson phenotype usually present with severe postural instability and falls, and eventually develop a vertical supranuclear gaze palsy that allows its diagnosis.

Feb 28, 2020 · The main motor symptoms of PD include bradykinesia and muscle rigidity, tremor, and postural instability.