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phys.org
Barcelona Institute of Science,Technology
Scientists decipher the keys underlying the differences between SMAD2 and SMAD3, two almost identical transcription factors but with distinct roles
Tri-dimensional change in the SMAD2 protein, from an open configuration that allows the transcription factor to bind to DNA (in green) to a closed configuration that is incompatible with such binding (in red). Credit: Pau Martín-Malpartida and Maria J. Macias, IRB Barcelona
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